ATG2A antibody (AA 700-800)

Catalog No. ABIN6137252

The Rabbit Polyclonal anti-ATG2A antibody has been validated for WB. It is suitable to detect ATG2A in samples from Human.

Quick Overview for ATG2A antibody (AA 700-800) (ABIN6137252)

Target: ATG2A (ATG2 Autophagy Related 2 Homolog A (S. Cerevisiae) (ATG2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG2A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ATG2A Antibody

Binding Specificity: AA 700-800

Sequence: DLHGIYEDGG KPPVPCLRVS KALDPKSTGR KYFLPQVVVT VNPQSSSTQW EVAPEKGEEL ELSVESPCEL REPEPSPFSS KRTMYETEEM VIPGDPEEMR T

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 700-800 of human ATG2A (NP_055919.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATG2A

Target: ATG2A (ATG2 Autophagy Related 2 Homolog A (S. Cerevisiae) (ATG2A))

Alternative Name: ATG2A

Background: Lipid transfer protein involved in autophagosome assembly. Tethers the edge of the isolation membrane (IM to the endoplasmic reticulum (ER and mediates direct lipid transfer from ER to IM for IM expansion. Binds to the ER exit site (ERES, which is the membrane source for autophagosome formation, and extracts phospholipids from the membrane source and transfers them to ATG9 (ATG9A or ATG9B to the IM for membrane expansion. Lipid transfer activity is enhanced by WIPI1 and WDR45/WIPI4, which promote ATG2A-association with phosphatidylinositol 3-monophosphate (PI3P-containing membranes. Also regulates lipid droplets morphology and distribution within the cell.,ATG2A,Endocrine & Metabolism,Mitochondrial metabolism,ATG2A

Molecular Weight: 13 kDa/35 kDa/212 kDa/213 kDa

Gene ID: 23130

UniProt: Q2TAZ0