MT-ATP6 antibody (C-Term)

Catalog No. ABIN6137340

The Rabbit Polyclonal anti-MT-ATP6 antibody has been validated for WB, IF and IHC. It is suitable to detect MT-ATP6 in samples from Mouse. There are 2+ publications available.

Quick Overview for MT-ATP6 antibody (C-Term) (ABIN6137340)

Target: MT-ATP6 (Mitochondrially Encoded ATP Synthase 6 (MT-ATP6))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MT-ATP6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-MT-ATP6 Antibody

Binding Specificity: C-Term

Sequence: MNLSMAIPLW AGAVITGFRH KLKSSLAHFL PQGTPISLIP MLIIIETISL FIQPMALAVR LTANITAGHL LMHLIGGATL VLMNISPPTA TITFIILLLL TILEFAVALI QAYVFTLLVS LYLHDNT

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of mouse ATP6 (NP_904333.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-MT-ATP6 antibody (ABIN6137340)

Li, Zhou, Li, Li, Long, Chen, Zhang, Li, Feng: "WITHDRAWN:Mitochondrial targeting of HIF-1α inhibits hypoxia-induced apoptosis independently of its transcriptional activity." in: Free radical biology & medicine, (2018) (PubMed).

Hu, Nie, Chen, Xie, Fan, Wang, Long, Yan, Zhong, Yan: "Leucine reduces reactive oxygen species levels via an energy metabolism switch by activation of the mTOR-HIF-1α pathway in porcine intestinal epithelial cells." in: The international journal of biochemistry & cell biology, Vol. 89, pp. 42-56, (2017) (PubMed).

Target Details for MT-ATP6

Target: MT-ATP6 (Mitochondrially Encoded ATP Synthase 6 (MT-ATP6))

Alternative Name: MT-ATP6

Background: Mitochondrial membrane ATP synthase (F(1F(0 ATP synthase or Complex V produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1 - containing the extramembraneous catalytic core and F(0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel, it may play a direct role in the translocation of protons across the membrane.,MT-ATP6,ATPase6,MTATP6,ATP6,Endocrine & Metabolism,Mitochondrial metabolism,Neuroscience,Neurodegenerative Diseases,MT-ATP6

Molecular Weight: 25 kDa

Gene ID: 17705

UniProt: P00848

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process