BAAT antibody (AA 309-418)

Catalog No. ABIN6137411

This Rabbit Polyclonal antibody specifically detects BAAT in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for BAAT antibody (AA 309-418) (ABIN6137411)

Target: BAAT (Bile Acid CoA: Amino Acid N-Acyltransferase (Glycine N-Choloyltransferase) (BAAT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAAT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-BAAT Antibody

Binding Specificity: AA 309-418

Sequence: YLFPIEEAQG QFLFIVGEGD KTINSKAHAE QAIGQLKRHG KNNWTLLSYP GAGHLIEPPY SPLCCASTTH DLRLHWGGEV IPHAAAQEHA WKEIQRFLRK HLIPDVTSQL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 309-418 of human BAAT (NP_001692.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BAAT

Target: BAAT (Bile Acid CoA: Amino Acid N-Acyltransferase (Glycine N-Choloyltransferase) (BAAT))

Alternative Name: BAAT

Background: The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.,BAAT,BACAT,BAT,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,BAAT

Molecular Weight: 46 kDa

Gene ID: 570

UniProt: Q14032