BMP15 antibody (AA 143-392)

Catalog No. ABIN6137593

This Rabbit Polyclonal antibody specifically detects BMP15 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for BMP15 antibody (AA 143-392) (ABIN6137593)

Target: BMP15 (Bone Morphogenetic Protein 15 (BMP15))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP15 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-BMP15 Antibody

Binding Specificity: AA 143-392

Sequence: LTRFNLSCHV EPWVQKNPTN HFPSSEGDSS KPSLMSNAWK EMDITQLVQQ RFWNNKGHRI LRLRFMCQQQ KDSGGLELWH GTSSLDIAFL LLYFNDTHKS IRKAKFLPRG MEEFMERESL LRRTRQADGI SAEVTASSSK HSGPENNQCS LHPFQISFRQ LGWDHWIIAP PFYTPNYCKG TCLRVLRDGL NSPNHAIIQN LINQLVDQSV PRPSCVPYKY VPISVLMIEA NGSILYKEYE GMIAESCTCR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 143-392 of human BMP15 (NP_005439.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BMP15

Target: BMP15 (Bone Morphogenetic Protein 15 (BMP15))

Alternative Name: BMP15

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure.,BMP15,GDF9B,ODG2,POF4,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Wnt/β-Catenin Signaling Pathway,Immunology & Inflammation,Cytokines,NF-kB Signaling Pathway,Stem Cells,Germline Stem Cells,Cardiovascular,Angiogenesis,BMP15

Molecular Weight: 45 kDa

Gene ID: 9210

UniProt: O95972