BNIP3L/NIX antibody (AA 1-187)

Catalog No. ABIN6137622

This anti-BNIP3L/NIX antibody is a Rabbit Polyclonal antibody detecting BNIP3L/NIX in WB, IHC and IF. Suitable for Human.

Quick Overview for BNIP3L/NIX antibody (AA 1-187) (ABIN6137622)

Target: BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BNIP3L/NIX antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-BNIP3L/NIX Antibody

Binding Specificity: AA 1-187

Sequence: MSSHLVEPPP PLHNNNNNCE ENEQSLPPPA GLNSSWVELP MNSSNGNDNG NGKNGGLEHV PSSSSIHNGD MEKILLDAQH ESGQSSSRGS SHCDSPSPQE DGQIMFDVEM HTSRDHSSQS EEEVVEGEKE VEALKKSADW VSDWSSRPEN IPPKEFHFRH PKRSVSLSMR KSGAMKKGGI FSAEFLK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-187 of human BNIP3L (NP_004322.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BNIP3L/NIX

Target: BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

Alternative Name: BNIP3L

Background: This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c.,BNIP3L,BNIP3a,NIX,Cancer,Tumor suppressors,p53 pathway,Invasion and Metastasis,Cell Biology & Developmental Biology,Apoptosis,Bcl 2 family,Autophagy,Wnt/β-Catenin Signaling Pathway,Endocrine & Metabolism,Mitochondrial metabolism,Mitophagy fission and fusion,Cardiovascular,Heart,Mitochondrial Control of Autophagy,BNIP3L

Molecular Weight: 19 kDa/23 kDa

Gene ID: 665

UniProt: O60238

Pathways: Autophagy