C5AR1 antibody (AA 250-350)

Catalog No. ABIN6137777

This anti-C5AR1 antibody is a Rabbit Polyclonal antibody detecting C5AR1 in WB and IHC. Suitable for Human.

Quick Overview for C5AR1 antibody (AA 250-350) (ABIN6137777)

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C5AR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-C5AR1 Antibody

Binding Specificity: AA 250-350

Sequence: SFFIFWLPYQ VTGIMMSFLE PSSPTFLLLN KLDSLCVSFA YINCCINPII YVVAGQGFQG RLRKSLPSLL RNVLTEESVV RESKSFTRST VDTMAQKTQA V

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 250-350 of human C5AR1 (NP_001727.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for C5AR1

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Alternative Name: C5AR1

Background: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.,C5AR1,C5A,C5AR,C5R1,CD88,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,C5AR1

Molecular Weight: 39 kDa

Gene ID: 728

UniProt: P21730

Pathways: Complement System