GPR77
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB,1:1000 - 1:2000
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
GPR77
(G Protein-Coupled Receptor 77 (GPR77))
Alternative Name
C5AR2
Background
This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants.,C5AR2,C5L2,GPF77,GPR77,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),C5AR2