CAPZB antibody (AA 1-272)

Catalog No. ABIN6137935

This Rabbit Polyclonal antibody specifically detects CAPZB in WB and IF. It exhibits reactivity toward Human.

Quick Overview for CAPZB antibody (AA 1-272) (ABIN6137935)

Target: CAPZB (Capping Protein (Actin Filament) Muscle Z-Line, beta (CAPZB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAPZB antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-CAPZB Antibody

Binding Specificity: AA 1-272

Sequence: MSDQQLDCAL DLMRRLPPQQ IEKNLSDLID LVPSLCEDLL SSVDQPLKIA RDKVVGKDYL LCDYNRDGDS YRSPWSNKYD PPLEDGAMPS ARLRKLEVEA NNAFDQYRDL YFEGGVSSVY LWDLDHGFAG VILIKKAGDG SKKIKGCWDS IHVVEVQEKS SGRTAHYKLT STVMLWLQTN KSGSGTMNLG GSLTRQMEKD ETVSDCSPHI ANIGRLVEDM ENKIRSTLNE IYFGKTKDIV NGLRSVQTFA DKSKQEALKN DLVEALKRKQ QC

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-272 of human CAPZB (NP_004921.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CAPZB

Target: CAPZB (Capping Protein (Actin Filament) Muscle Z-Line, beta (CAPZB))

Alternative Name: CAPZB

Background: This gene encodes the beta subunit of the barbed-end actin binding protein, which belongs to the F-actin capping protein family. The capping protein is a heterodimeric actin capping protein that blocks actin filament assembly and disassembly at the fast growing (barbed) filament ends and functions in regulating actin filament dynamics as well as in stabilizing actin filament lengths in muscle and nonmuscle cells. A pseudogene of this gene is located on the long arm of chromosome 2. Multiple alternatively spliced transcript variants encoding different isoforms have been found.,CAPZB,CAPB,CAPPB,CAPZ,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,CAPZB

Molecular Weight: 30 kDa/31 kDa

Gene ID: 832

UniProt: P47756

Pathways: Regulation of Actin Filament Polymerization