CCT4 antibody (AA 130-390)
Quick Overview for CCT4 antibody (AA 130-390) (ABIN6138108)
Target
See all CCT4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 130-390
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Sequence
- PTIISESFQK ALEKGIEILT DMSRPVELSD RETLLNSATT SLNSKVVSQY SSLLSPMSVN AVMKVIDPAT ATSVDLRDIK IVKKLGGTID DCELVEGLVL TQKVSNSGIT RVEKAKIGLI QFCLSAPKTD MDNQIVVSDY AQMDRVLREE RAYILNLVKQ IKKTGCNVLL IQKSILRDAL SDLALHFLNK MKIMVIKDIE REDIEFICKT IGTKPVAHID QFTADMLGSA ELAEEVNLNG SGKLLKITGC ASPGKTVTIV V
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 130-390 of human CCT4 (NP_006421.2).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Comment
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- CCT4 (Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4))
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Alternative Name
- CCT4
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Background
- The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).[supplied by OMIM, Mar 2008],CCT4,CCT-DELTA,Cctd,SRB,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,CCT4
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Molecular Weight
- 54 kDa/57 kDa
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Gene ID
- 10575
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UniProt
- P50991
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Pathways
- Embryonic Body Morphogenesis
Target
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