CD177 antibody (AA 35-285)

Catalog No. ABIN6138125

This anti-CD177 antibody is a Rabbit Polyclonal antibody detecting CD177 in WB. Suitable for Human.

Quick Overview for CD177 antibody (AA 35-285) (ABIN6138125)

Target: CD177 (CD177 Molecule (CD177))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD177 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD177 Antibody

Binding Specificity: AA 35-285

Sequence: VSDLPRQWTP KNTSCDSGLG CQDTLMLIES GPQVSLVLSK GCTEAKDQEP RVTEHRMGPG LSLISYTFVC RQEDFCNNLV NSLPLWAPQP PADPGSLRCP VCLSMEGCLE GTTEEICPKG TTHCYDGLLR LRGGGIFSNL RVQGCMPQPV CNLLNGTQEI GPVGMTENCD MKDFLTCHRG TTIMTHGNLA QEPTDWTTSN TEMCEVGQVC QETLLLLDVG LTSTLVGTKG CSTVGAQNSQ KTTIHSAPPG V

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 35-285 of human CD177 (NP_065139.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CD177

Target: CD177 (CD177 Molecule (CD177))

Alternative Name: CD177

Background: This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.,CD177,HNA-2a,HNA2A,NB1,NB1 GP,PRV-1,PRV1,NB1GP,Immunology & Inflammation,CD markers,CD177

Molecular Weight: 15 kDa/27 kDa/46 kDa

Gene ID: 57126

UniProt: Q8N6Q3