CD1b antibody (AA 18-303)

Catalog No. ABIN6138133

This Rabbit Polyclonal antibody specifically detects CD1b in WB. It exhibits reactivity toward Human.

Quick Overview for CD1b antibody (AA 18-303) (ABIN6138133)

Target: CD1b (CD1B)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD1b antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD1b Antibody

Binding Specificity: AA 18-303

Sequence: SEHAFQGPTS FHVIQTSSFT NSTWAQTQGS GWLDDLQIHG WDSDSGTAIF LKPWSKGNFS DKEVAELEEI FRVYIFGFAR EVQDFAGDFQ MKYPFEIQGI AGCELHSGGA IVSFLRGALG GLDFLSVKNA SCVPSPEGGS RAQKFCALII QYQGIMETVR ILLYETCPRY LLGVLNAGKA DLQRQVKPEA WLSSGPSPGP GRLQLVCHVS GFYPKPVWVM WMRGEQEQQG TQLGDILPNA NWTWYLRATL DVADGEAAGL SCRVKHSSLE GQDIILYWRN PTSIGS

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 18-303 of human CD1B (NP_001755.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CD1b

Target: CD1b (CD1B)

Alternative Name: CD1B

Background: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.,CD1B,CD1,CD1A,R1,Immunology & Inflammation,CD markers,CD1B

Molecular Weight: 30 kDa/36 kDa

Gene ID: 910

UniProt: P29016