CD207 antibody (AA 69-328)

Catalog No. ABIN6138141

This Rabbit Polyclonal antibody specifically detects CD207 in WB. It exhibits reactivity toward Human.

Quick Overview for CD207 antibody (AA 69-328) (ABIN6138141)

Target: CD207 (CD207 Molecule, Langerin (CD207))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD207 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD207 Antibody

Binding Specificity: AA 69-328

Sequence: GTISDVKTNV QLLKGRVDNI STLDSEIKKN SDGMEAAGVQ IQMVNESLGY VRSQFLKLKT SVEKANAQIQ ILTRSWEEVS TLNAQIPELK SDLEKASALN TKIRALQGSL ENMSKLLKRQ NDILQVVSQG WKYFKGNFYY FSLIPKTWYS AEQFCVSRNS HLTSVTSESE QEFLYKTAGG LIYWIGLTKA GMEGDWSWVD DTPFNKVQSV RFWIPGEPNN AGNNEHCGNI KAPSLQAWND APCDKTFLFI CKRPYVPSEP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 69-328 of human CD207 (NP_056532.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CD207

Target: CD207 (CD207 Molecule, Langerin (CD207))

Alternative Name: CD207

Background: The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.,CD207,CLEC4K,Cancer,Signal Transduction,Endocrine & Metabolism,Immunology & Inflammation,CD markers,CD207

Molecular Weight: 36 kDa

Gene ID: 50489

UniProt: Q9UJ71