CD207 antibody (AA 69-328)
CD207
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
1 image
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- Target See all CD207 Antibodies
- CD207 (CD207 Molecule, Langerin (CD207))
- Binding Specificity
- AA 69-328
- Reactivity
- Human
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Western Blotting (WB)
- Sequence
- GTISDVKTNV QLLKGRVDNI STLDSEIKKN SDGMEAAGVQ IQMVNESLGY VRSQFLKLKT SVEKANAQIQ ILTRSWEEVS TLNAQIPELK SDLEKASALN TKIRALQGSL ENMSKLLKRQ NDILQVVSQG WKYFKGNFYY FSLIPKTWYS AEQFCVSRNS HLTSVTSESE QEFLYKTAGG LIYWIGLTKA GMEGDWSWVD DTPFNKVQSV RFWIPGEPNN AGNNEHCGNI KAPSLQAWND APCDKTFLFI CKRPYVPSEP
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 69-328 of human CD207 (NP_056532.4).
- Isotype
- IgG
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- Application Notes
- WB,1:500 - 1:2000
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CD207 (CD207 Molecule, Langerin (CD207))
- Alternative Name
- CD207
- Background
- The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.,CD207,CLEC4K,Cancer,Signal Transduction,Endocrine & Metabolism,Immunology & Inflammation,CD markers,CD207
- Molecular Weight
- 36 kDa
- Gene ID
- 50489
- UniProt
- Q9UJ71
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