Cadherin-16 antibody (AA 19-230)

Catalog No. ABIN6138291

The Rabbit Polyclonal anti-Cadherin-16 antibody has been validated for IHC, WB and IF. It is suitable to detect Cadherin-16 in samples from Human.

Quick Overview for Cadherin-16 antibody (AA 19-230) (ABIN6138291)

Target: Cadherin-16 (CDH16)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin-16 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Cadherin-16 Antibody

Binding Specificity: AA 19-230

Sequence: KAQPAELSVE VPENYGGNFP LYLTKLPLPR EGAEGQIVLS GDSGKATEGP FAMDPDSGFL LVTRALDREE QAEYQLQVTL EMQDGHVLWG PQPVLVHVKD ENDQVPHFSQ AIYRARLSRG TRPGIPFLFL EASDRDEPGT ANSDLRFHIL SQAPAQPSPD MFQLEPRLGA LALSPKGSTS LDHALERTYQ LLVQVKDMGD QASGHQATAT VE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 19-230 of human Cadherin 16 (NP_004053.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Cadherin-16

Target: Cadherin-16 (CDH16)

Alternative Name: CDH16

Background: This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.,CDH16,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cadherins,Cytoskeleton,CDH16

Molecular Weight: 79 kDa/85 kDa/87 kDa/89 kDa

Gene ID: 1014

UniProt: O75309