CHRM3 antibody (AA 390-475)

Catalog No. ABIN6138565

The Rabbit Polyclonal anti-CHRM3 antibody has been validated for WB. It is suitable to detect CHRM3 in samples from Human. There is 1 publication available.

Quick Overview for CHRM3 antibody (AA 390-475) (ABIN6138565)

Target: CHRM3 (Cholinergic Receptor, Muscarinic 3 (CHRM3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRM3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHRM3 Antibody

Binding Specificity: AA 390-475

Sequence: QVPEEELGMV DLERKADKLQ AQKSVDDGGS FPKSFSKLPI QLESAVDTAK TSDVNSSVGK STATLPLSFK EATLAKRFAL KTRSQI

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 390-475 of human CHRM3 (NP_000731.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-CHRM3 antibody (ABIN6138565)

Lasisi, Shittu, Alada: "Re-establishing normal diet following high fat-diet-induced obesity reverses the altered salivary composition in Wistar rats." in: Journal of basic and clinical physiology and pharmacology, (2018) (PubMed).

Target Details for CHRM3

Target: CHRM3 (Cholinergic Receptor, Muscarinic 3 (CHRM3))

Alternative Name: CHRM3

Background: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue.,CHRM3,EGBRS,HM3,PBS,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CHRM3

Molecular Weight: 66 kDa

Gene ID: 1131

UniProt: P20309

Pathways: Synaptic Membrane