Claudin 3 antibody (AA 141-220)

Catalog No. ABIN6138688

This Rabbit Polyclonal antibody specifically detects Claudin 3 in WB. It exhibits reactivity toward Human.

Quick Overview for Claudin 3 antibody (AA 141-220) (ABIN6138688)

Target: Claudin 3 (CLDN3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Claudin 3 Antibody

Binding Specificity: AA 141-220

Sequence: TIIRDFYNPV VPEAQKREMG AGLYVGWAAA ALQLLGGALL CCSCPPREKK YTATKVVYSA PRSTGPGASL GTGYDRKDYV

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 141-220 of human CLDN3 (NP_001297.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Claudin 3

Target: Claudin 3 (CLDN3)

Alternative Name: CLDN3

Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.,CLDN3,C7orf1,CPE-R2,CPETR2,HRVP1,RVP1,claudin-3,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,Endocrine & Metabolism,CLDN3

Molecular Weight: 23 kDa

Gene ID: 1365

UniProt: O15551

Pathways: Hepatitis C