CLEC7A antibody (C-Term)

Catalog No. ABIN6138717

Product Details anti-CLEC7A Antibody

Target: CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLEC7A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LEDSVTPTKA VKTTGVLSSP CPPNWIIYEK SCYLFSMSLN SWDGSKRQCW QLGSNLLKID SSNELGFIVK QVSSQPDNSF WIGLSRPQTE VPWLWEDGST FSSNLFQIRT TATQENPSPN CVWIHVSVIY DQLCSVPSYS ICEKKFSM

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human CLEC7A (NP_922938.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CLEC7A

Target: CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))

Alternative Name: CLEC7A (CLEC7A Products)

Background: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.,CLEC7A,BGR,CANDF4,CD369,CLECSF12,DECTIN1,SCARE2,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,CLEC7A

Molecular Weight: 5 kDa/8 kDa/13-27 kDa

Gene ID: 64581

UniProt: Q9BXN2

Pathways: Activation of Innate immune Response