Coilin antibody (AA 297-576)

Catalog No. ABIN6138829

The Rabbit Polyclonal anti-Coilin antibody has been validated for WB and IP. It is suitable to detect Coilin in samples from Human.

Quick Overview for Coilin antibody (AA 297-576) (ABIN6138829)

Target: Coilin (COIL)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Coilin antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-Coilin Antibody

Binding Specificity: AA 297-576

Sequence: KLGFSLTPSK GKTSGTTSSS SDSSAESDDQ CLMSSSTPEC AAGFLKTVGL FAGRGRPGPG LSSQTAGAAG WRRSGSNGGG QAPGASPSVS LPASLGRGWG REENLFSWKG AKGRGMRGRG RGRGHPVSCV VNRSTDNQRQ QQLNDVVKNS STIIQNPVET PKKDYSLLPL LAAAPQVGEK IAFKLLELTS SYSPDVSDYK EGRILSHNPE TQQVDIEILS SLPALREPGK FDLVYHNENG AEVVEYAVTQ ESKITVFWKE LIDPRLIIES PSNTSSTEPA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 297-576 of human Coilin (NP_004636.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IP,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Coilin

Target: Coilin (COIL)

Alternative Name: COIL

Background: The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.,COIL,CLN80,p80-coilin,coilin,Coilin,Epigenetics & Nuclear Signaling,Neuroscience,Cell Type Marker,Neuron marker,COIL

Molecular Weight: 62 kDa

Gene ID: 8161

UniProt: P38432

Pathways: Ribonucleoprotein Complex Subunit Organization