COLEC12 antibody (AA 60-270)

Catalog No. ABIN6138857

This anti-COLEC12 antibody is a Rabbit Polyclonal antibody detecting COLEC12 in WB. Suitable for Human.

Quick Overview for COLEC12 antibody (AA 60-270) (ABIN6138857)

Target: COLEC12 (Collectin Sub-Family Member 12 (COLEC12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COLEC12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COLEC12 Antibody

Binding Specificity: AA 60-270

Sequence: KVVEKMDNVT GGMETSRQTY DDKLTAVESD LKKLGDQTGK KAISTNSELS TFRSDILDLR QQLREITEKT SKNKDTLEKL QASGDALVDR QSQLKETLEN NSFLITTVNK TLQAYNGYVT NLQQDTSVLQ GNLQNQMYSH NVVIMNLNNL NLTQVQQRNL ITNLQRSVDD TSQAIQRIKN DFQNLQQVFL QAKKDTDWLK EKVQSLQTLA A

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-270 of human COLEC12 (NP_569057.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COLEC12

Target: COLEC12 (Collectin Sub-Family Member 12 (COLEC12))

Alternative Name: COLEC12

Background: This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells.,COLEC12,CLP1,NSR2,SCARA4,SRCL,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,COLEC12

Molecular Weight: 81 kDa

Gene ID: 81035

UniProt: Q5KU26

Pathways: Activation of Innate immune Response