COX6A1 antibody (AA 25-109)

Catalog No. ABIN6138915

The Rabbit Polyclonal anti-COX6A1 antibody (ABIN6138915) specifically detects COX6A1 in WB, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for COX6A1 antibody (AA 25-109) (ABIN6138915)

Target: COX6A1 (Cytochrome C Oxidase Subunit VIa Polypeptide 1 (COX6A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX6A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-COX6A1 Antibody

Binding Specificity: AA 25-109

Sequence: SSGAHGEEGS ARMWKTLTFF VALPGVAVSM LNVYLKSHHG EHERPEFIAY PHLRIRTKPF PWGDGNHTLF HNPHVNPLPT GYEDE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-109 of human COX6A1 (NP_004364.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IHC,1:20 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COX6A1

Target: COX6A1 (Cytochrome C Oxidase Subunit VIa Polypeptide 1 (COX6A1))

Alternative Name: COX6A1

Background: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66 % amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented.,COX6A1,CMTRID,COX6A,COX6AL,Endocrine & Metabolism,Mitochondrial metabolism,Oxidative phosphorylation,Neuroscience,Neurodegenerative Diseases,COX6A1

Molecular Weight: 12 kDa

Gene ID: 1337

UniProt: P12074