CRLF2 antibody (AA 23-231)

Catalog No. ABIN6139052

The Rabbit Polyclonal anti-CRLF2 antibody has been validated for WB. It is suitable to detect CRLF2 in samples from Human.

Quick Overview for CRLF2 antibody (AA 23-231) (ABIN6139052)

Target: CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRLF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CRLF2 Antibody

Binding Specificity: AA 23-231

Sequence: QGGAAEGVQI QIIYFNLETV QVTWNASKYS RTNLTFHYRF NGDEAYDQCT NYLLQEGHTS GCLLDAEQRD DILYFSIRNG THPVFTASRW MVYYLKPSSP KHVRFSWHQD AVTVTCSDLS YGDLLYEVQY RSPFDTEWQS KQENTCNVTI EGLDAEKCYS FWVRVKAMED VYGPDTYPSD WSEVTCWQRG EIRDACAETP TPPKPKLSK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 23-231 of human CRLF2 (NP_071431.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:1000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CRLF2

Target: CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

Alternative Name: CRLF2

Background: This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.,CRLF2,CRL2,CRLF2Y,TSLPR,Immunology & Inflammation,Cytokines,Cell Intrinsic Innate Immunity Signaling Pathway,CRLF2

Molecular Weight: 26 kDa/29 kDa/42 kDa

Gene ID: 64109

UniProt: Q9HC73