CRY2 antibody (AA 455-614)

Catalog No. ABIN6139068

This Rabbit Polyclonal antibody specifically detects CRY2 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for CRY2 antibody (AA 455-614) (ABIN6139068)

Target: CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRY2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-CRY2 Antibody

Binding Specificity: AA 455-614

Sequence: PVGFGRRTDP SGDYIRRYLP KLKAFPSRYI YEPWNAPESI QKAAKCIIGV DYPRPIVNHA ETSRLNIERM KQIYQQLSRY RGLCLLASVP SCVEDLSHPV AEPSSSQAGS MSSAGPRPLP SGPASPKRKL EAAEEPPGEE LSKRARVAEL PTPELPSKDA

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 455-614 of human CRY2 (NP_066940.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CRY2

Target: CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))

Alternative Name: CRY2

Background: This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene.,CRY2,HCRY2,PHLL2,Neuroscience,Cardiovascular,Blood,Blood Pressure regulation,CRY2

Molecular Weight: 60 kDa/66 kDa

Gene ID: 1408

UniProt: Q49AN0

Pathways: Response to Water Deprivation, Protein targeting to Nucleus