DARS2 antibody (AA 406-645)

Catalog No. ABIN6139409

This Rabbit Polyclonal antibody specifically detects DARS2 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for DARS2 antibody (AA 406-645) (ABIN6139409)

Target: DARS2 (Aspartyl-tRNA Synthetase 2, Mitochondrial (DARS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DARS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-DARS2 Antibody

Binding Specificity: AA 406-645

Sequence: ANRNWNSPVA NFIMESQRLE LIRLMETQEE DVVLLTAGEH NKACSLLGKL RLECADLLET RGVVLRDPTL FSFLWVVDFP LFLPKEENPR ELESAHHPFT APHPSDIHLL YTEPKKARSQ HYDLVLNGNE IGGGSIRIHN AELQRYILAT LLKEDVKMLS HLLQALDYGA PPHGGIALGL DRLICLVTGS PSIRDVIAFP KSFRGHDLMS NTPDSVPPEE LKPYHIRVSK PTDSKAERAH

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 406-645 of human DARS2 (NP_060592.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DARS2

Target: DARS2 (Aspartyl-tRNA Synthetase 2, Mitochondrial (DARS2))

Alternative Name: DARS2

Background: The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL).,DARS2,ASPRS,LBSL,MT-ASPRS,Epigenetics & Nuclear Signaling,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Mitochondrial translation,Nucleotide metabolism,DARS2

Molecular Weight: 73 kDa

Gene ID: 55157

UniProt: Q6PI48