DBN1 antibody (AA 350-649)

Catalog No. ABIN6139424

This anti-DBN1 antibody is a Rabbit Polyclonal antibody detecting DBN1 in WB and IF. Suitable for Human.

Quick Overview for DBN1 antibody (AA 350-649) (ABIN6139424)

Target: DBN1 (Drebrin 1 (DBN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DBN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-DBN1 Antibody

Binding Specificity: AA 350-649

Sequence: EQIERALDEV TSSQPPPLPP PPPPAQETQE PSPILDSEET RAAAPQAWAG PMEEPPQAQA PPRGPGSPAE DLMFMESAEQ AVLAAPVEPA TADATEIHDA ADTIETDTAT ADTTVANNVP PAATSLIDLW PGNGEGASTL QGEPRAPTPP SGTEVTLAEV PLLDEVAPEP LLPAGEGCAT LLNFDELPEP PATFCDPEEV EGEPLAAPQT PTLPSALEEL EQEQEPEPHL LTNGETTQKE GTQASEGYFS QSQEEEFAQS EELCAKAPPP VFYNKPPEID ITCWDADPVP EEEEGFEGGD

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 350-649 of human DBN1 (NP_004386.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DBN1

Target: DBN1 (Drebrin 1 (DBN1))

Alternative Name: DBN1

Background: The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.,DBN1,D0S117E,drebrin,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Cytoskeleton,Microfilaments,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Neuron marker,Dendrite marker,Growth Cone,DBN1

Molecular Weight: 71 kDa/76 kDa

Gene ID: 1627

UniProt: Q16643

Pathways: Maintenance of Protein Location