DGCR14 antibody (AA 1-300)

Catalog No. ABIN6139562

This Rabbit Polyclonal antibody specifically detects DGCR14 in WB. It exhibits reactivity toward Human.

Quick Overview for DGCR14 antibody (AA 1-300) (ABIN6139562)

Target: DGCR14 (DiGeorge Syndrome Critical Region Gene 14 (DGCR14))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DGCR14 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DGCR14 Antibody

Binding Specificity: AA 1-300

Sequence: METPGASASS LLLPAASRPP RKREAGEAGA ATSKQRVLDE EEYIEGLQTV IQRDFFPDVE KLQAQKEYLE AEENGDLERM RQIAIKFGSA LGKMSREPPP PYVTPATFET PEVHAGTGVV GNKPRPRGRG LEDGEAGEEE EKEPLPSLDV FLSRYTSEDN ASFQEIMEVA KERSRARHAW LYQAEEEFEK RQKDNLELPS AEHQAIESSQ ASVETWKYKA KNSLMYYPEG VPDEEQLFKK PRQVVHKNTR FLRDPFSQAL SRCQLQQAAA LNAQHKQGKV GPDGKELIPQ ESPRVGGFGF

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DGCR14 (NP_073210.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DGCR14

Target: DGCR14 (DiGeorge Syndrome Critical Region Gene 14 (DGCR14))

Alternative Name: DGCR14

Background: This gene is located within the minimal DGS critical region (MDGCR) thought to contain the gene(s) responsible for a group of developmental disorders. These disorders include DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome, and some familial or sporadic conotruncal cardiac defects which have been associated with microdeletion of 22q11.2. The encoded protein may be a component of C complex spliceosomes, and the orthologous protein in the mouse localizes to the nucleus. Alternatively spliced transcript variants have been found for this gene.,DGCR14,DGCR13,DGS-H,DGS-I,DGSH,DGSI,ES2,ESS-2,Es2el,bis1,DGCR14

Molecular Weight: 52 kDa

Gene ID: 8220

UniProt: Q96DF8