DGCR14 antibody (AA 426-476)

Catalog No. ABIN7450986

Product Details anti-DGCR14 Antibody

Target: DGCR14 (DiGeorge Syndrome Critical Region Gene 14 (DGCR14))

Binding Specificity: AA 426-476

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DGCR14 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-DGCR14 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 426 and 476

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:500 - 1:2,500

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DGCR14

Target: DGCR14 (DiGeorge Syndrome Critical Region Gene 14 (DGCR14))

Alternative Name: DGCR14 (DGCR14 Products)

Synonyms: DGCR13 antibody, DGS-H antibody, DGS-I antibody, DGSH antibody, DGSI antibody, ES2 antibody, Es2el antibody, AI462402 antibody, D16H22S1269E antibody, Dgcr1 antibody, Dgsi antibody, fc19d10 antibody, wu:fc19d10 antibody, zgc:162979 antibody, MGC82189 antibody, DGCR14 antibody, es2 antibody, dgsi antibody, dgs-h antibody, dgs-i antibody, es2el antibody, dgcr13 antibody, ess-2 splicing factor homolog antibody, DiGeorge syndrome critical region gene 14 antibody, ess-2 splicing factor homolog S homeolog antibody, ESS2 antibody, Dgcr14 antibody, ess2 antibody, Ess2 antibody, DGCR14 antibody, ess2.S antibody

Background: Background: The gene encoding DGCR14 (DiGeorge syndrome critical region gene 14) is located within the minimal DGS critical region (MDGCR) thought to contain the gene(s) responsible for a group of developmental disorders. These disorders include DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome, and some familial or sporadic conotruncal cardiac defects which have been associated with microdeletion of 22q11.2. The DGCR14 protein may be a component of C complex spliceosomes, and the orthologous protein in the mouse localizes to the nucleus [taken from NCBI Entrez Gene (Gene ID: 8220)].

Gene ID: 8220

NCBI Accession: NP_073210

UniProt: Q96DF8