DISC1 antibody (AA 1-200)

Catalog No. ABIN6139633

This Rabbit Polyclonal antibody specifically detects DISC1 in WB. It exhibits reactivity toward Human.

Quick Overview for DISC1 antibody (AA 1-200) (ABIN6139633)

Target: DISC1 (Disrupted in Schizophrenia 1 (DISC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DISC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DISC1 Antibody

Binding Specificity: AA 1-200

Sequence: MPGGGPQGAP AAAGGGGVSH RAGSRDCLPP AACFRRRRLA RRPGYMRSST GPGIGFLSPA VGTLFRFPGG VSGEESHHSE SRARQCGLDS RGLLVRSPVS KSAAAPTVTS VRGTSAHFGI QLRGGTRLPD RLSWPCGPGS AGWQQEFAAM DSSETLDASW EAACSDGARR VRAAGSLPSA ELSSNSCSPG CGPEVPPTPP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human DISC1 (NP_001158009.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DISC1

Target: DISC1 (Disrupted in Schizophrenia 1 (DISC1))

Alternative Name: DISC1

Background: This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1,11)(q42.1,q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.,DISC1,C1orf136,SCZD9,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,DISC1

Molecular Weight: 22 kDa/37-38 kDa/6-93 kDa

Gene ID: 27185

UniProt: Q9NRI5

Pathways: Regulation of Cell Size