DISC1 antibody

Catalog No. ABIN7266799

This Rabbit Monoclonal antibody specifically detects DISC1 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for DISC1 antibody (ABIN7266799)

Target: DISC1 (Disrupted in Schizophrenia 1 (DISC1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This DISC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-DISC1 Antibody

Purpose: DISC1 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human DISC1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DISC1

Target: DISC1 (Disrupted in Schizophrenia 1 (DISC1))

Alternative Name: DISC1

Background: This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1,11)(q42.1,q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],C1orf136, SCZD9,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Centrosome,Epigenetics & Nuclear Signaling,Neurodegenerative Diseases,Neurodegenerative Diseases_Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease,Neuroscience,DISC1

Molecular Weight: 100kDa

Gene ID: 27185

UniProt: Q9NRI5

Pathways: Regulation of Cell Size