DOK5 antibody (AA 237-306)

Catalog No. ABIN6139769

The Rabbit Polyclonal anti-DOK5 antibody has been validated for WB. It is suitable to detect DOK5 in samples from Human.

Quick Overview for DOK5 antibody (AA 237-306) (ABIN6139769)

Target: DOK5 (Docking Protein 5 (DOK5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DOK5 Antibody

Binding Specificity: AA 237-306

Sequence: LLQSVKNSML QMKMSERAAS LSTMVPLPRS AYWQHITRQH STGQLYRLQD VSSPLKLHRT ETFPAYRSEH

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 237-306 of human DOK5 (NP_060901.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DOK5

Target: DOK5 (Docking Protein 5 (DOK5))

Alternative Name: DOK5

Background: The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants.,DOK5,C20orf180,IRS-6,IRS6,Signal Transduction,Kinase,Tyrosine kinases,DOK5

Molecular Weight: 22 kDa/35 kDa

Gene ID: 55816

UniProt: Q9P104