DUSP5 antibody (AA 315-384)

Catalog No. ABIN6139875

This anti-DUSP5 antibody is a Rabbit Polyclonal antibody detecting DUSP5 in WB. Suitable for Human.

Quick Overview for DUSP5 antibody (AA 315-384) (ABIN6139875)

Target: DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DUSP5 Antibody

Binding Specificity: AA 315-384

Sequence: SEILPSTPNP QPPSCQGEAA GSSLIGHLQT LSPDMQGAYC TFPASVLAPV PTHSTVSELS RSPVATATSC

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 315-384 of human DUSP5 (NP_004410.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DUSP5

Target: DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))

Alternative Name: DUSP5

Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.,DUSP5,DUSP,HVH3,Signal Transduction,DUSP5

Molecular Weight: 42 kDa

Gene ID: 1847

UniProt: Q16690