E2F3 antibody (AA 200-300)

Catalog No. ABIN6139901

This anti-E2F3 antibody is a Rabbit Polyclonal antibody detecting E2F3 in WB. Suitable for Human.

Quick Overview for E2F3 antibody (AA 200-300) (ABIN6139901)

Target: E2F3

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This E2F3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-E2F3 Antibody

Binding Specificity: AA 200-300

Sequence: SIESLQIHLA STQGPIEVYL CPEETETHSP MKTNNQDHNG NIPKPASKDL ASTNSGHSDC SVSMGNLSPL ASPANLLQQT EDQIPSNLEG PFVNLLPPLL Q

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human E2F3 (NP_001230005.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for E2F3

Target: E2F3

Background: This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants.,E2F3,E2F-3,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,ErbB-HER Signaling Pathway,E2F3

Molecular Weight: 37 kDa/49 kDa

Gene ID: 1871

UniProt: O00716