EIF4B antibody (AA 352-611)

Catalog No. ABIN6140078

The Rabbit Polyclonal anti-EIF4B antibody has been validated for WB. It is suitable to detect EIF4B in samples from Human.

Quick Overview for EIF4B antibody (AA 352-611) (ABIN6140078)

Target: EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF4B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EIF4B Antibody

Binding Specificity: AA 352-611

Sequence: SQSTRAASIF GGAKPVDTAA REREVEERLQ KEQEKLQRQL DEPKLERRPR ERHPSWRSEE TQERERSRTG SESSQTGTST TSSRNARRRE SEKSLENETL NKEEDCHSPT SKPPKPDQPL KVMPAPPPKE NAWVKRSSNP PARSQSSDTE QQSPTSGGGK VAPAQPSEEG PGRKDENKVD GMNAPKGQTG NSSRGPGDGG NRDHWKESDR KDGKKDQDSR SAPEPKKPEE NPASKFSSAS KYAALSVDGE DENEGEDYAE

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 352-611 of human EIF4B (NP_001408.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EIF4B

Target: EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))

Alternative Name: EIF4B

Background: Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.,EIF4B,EIF-4B,PRO1843,Epigenetics & Nuclear Signaling,RNA Binding,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,MAPK-Erk Signaling Pathway,EIF4B

Molecular Weight: 64 kDa/69 kDa

Gene ID: 1975

UniProt: P23588