ERAL1 antibody (AA 198-437)

Catalog No. ABIN6140241

The Rabbit Polyclonal anti-ERAL1 antibody has been validated for WB. It is suitable to detect ERAL1 in samples from Human.

Quick Overview for ERAL1 antibody (AA 198-437) (ABIN6140241)

Target: ERAL1 (Era G-Protein-Like 1 (ERAL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERAL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ERAL1 Antibody

Binding Specificity: AA 198-437

Sequence: DLVVVLVDVS DKWTRNQLSP QLLRCLTKYS QIPSVLVMNK VDCLKQKSVL LELTAALTEG VVNGKKLKMR QAFHSHPGTH CPSPAVKDPN TQSVGNPQRI GWPHFKEIFM LSALSQEDVK TLKQYLLTQA QPGPWEYHSA VLTSQTPEEI CANIIREKLL EHLPQEVPYN VQQKTAVWEE GPGGELVIQQ KLLVPKESYV KLLIGPKGHV ISQIAQEAGH DLMDIFLCDV DIRLSVKLLK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 198-437 of human ERAL1 (NP_005693.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ERAL1

Target: ERAL1 (Era G-Protein-Like 1 (ERAL1))

Alternative Name: ERAL1

Background: The protein encoded by this gene is a GTPase that localizes to the mitochondrion. The encoded protein binds to the 3' terminal stem loop of 12S mitochondrial rRNA and is required for proper assembly of the 28S small mitochondrial ribosomal subunit. Deletion of this gene has been shown to cause mitochondrial dysfunction, growth retardation, and apoptosis. Several transcript variants encoding different isoforms have been found for this gene.,ERAL1,CEGA,ERA,ERA-W,ERAL1A,H-ERA,HERA-A,HERA-B,GTPase Era,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,ERAL1

Molecular Weight: 30 kDa/48 kDa

Gene ID: 26284

UniProt: O75616

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly