ETHE1 antibody (AA 8-245)

Catalog No. ABIN6140319

This Rabbit Polyclonal antibody specifically detects ETHE1 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for ETHE1 antibody (AA 8-245) (ABIN6140319)

Target: ETHE1 (Ethylmalonic Encephalopathy 1 (ETHE1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ETHE1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ETHE1 Antibody

Binding Specificity: AA 8-245

Sequence: VARRQLSQRG GSGAPILLRQ MFEPVSCTFT YLLGDRESRE AVLIDPVLET APRDAQLIKE LGLRLLYAVN THCHADHITG SGLLRSLLPG CQSVISRLSG AQADLHIEDG DSIRFGRFAL ETRASPGHTP GCVTFVLNDH SMAFTGDALL IRGCGRTDFQ QGCAKTLYHS VHEKIFTLPG DCLIYPAHDY HGFTVSTVEE ERTLNPRLTL SCEEFVKIMG NLNLPKPQQI DFAVPANM

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 8-245 of human ETHE1 (NP_055112.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:1000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ETHE1

Target: ETHE1 (Ethylmalonic Encephalopathy 1 (ETHE1))

Alternative Name: ETHE1

Background: This gene encodes a member of the metallo beta-lactamase family of iron-containing proteins involved in the mitochondrial sulfide oxidation pathway. The encoded protein catalyzes the oxidation of a persulfide substrate to sulfite. Certain mutations in this gene cause ethylmalonic encephalopathy, an infantile metabolic disorder affecting the brain, gastrointestinal tract and peripheral vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.,ETHE1,HSCO,YF13H12,Cancer,Tumor suppressors,p53 pathway,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,ETHE1

Molecular Weight: 27 kDa

Gene ID: 23474

UniProt: O95571