Envoplakin antibody (AA 1784-2033)
Quick Overview for Envoplakin antibody (AA 1784-2033) (ABIN6140350)
Target
See all Envoplakin (EVPL) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1784-2033
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Sequence
- TKPSSSLSIG SIISKSPLAS PAPQSTSFFS PSFSLGLGDD SFPIAGIYDT TTDNKCSIKT AVAKNMLDPI TGQKLLEAQA ATGGIVDLLS RERYSVHKAM ERGLIENTST QRLLNAQKAF TGIEDPVTKK RLSVGEAVQK GWMPRESVLP HLQVQHLTGG LIDPKRTGRI PIQQALLSGM ISEELAQLLQ DESSYEKDLT DPISKERLSY KEAMGRCRKD PLSGLLLLPA ALEGYRCYRS ASPTVPRSLR
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1784-2033 of human EVPL (NP_001979.2).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Comment
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Envoplakin (EVPL)
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Alternative Name
- EVPL
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Background
- This gene encodes a member of the plakin family of proteins that forms a component of desmosomes and the epidermal cornified envelope. This gene is located in the tylosis oesophageal cancer locus on chromosome 17q25, and its deletion is associated with both familial and sporadic forms of oesophageal squamous cell carcinoma. Patients suffering from the autoimmune mucocutaneous disorder, paraneoplastic pemphigus, develop antibodies against the encoded protein.,EVPL,EVPK,EVPL
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Molecular Weight
- 231 kDa
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Gene ID
- 2125
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UniProt
- Q92817
Target
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