Envoplakin antibody (AA 1275-1325)
Quick Overview for Envoplakin antibody (AA 1275-1325) (ABIN7449223)
Target
See all Envoplakin (EVPL) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1275-1325
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Purpose
- Rabbit anti-EVPL Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- Between AA 1275 and 1325
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Isotype
- IgG
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Application Notes
- 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- Envoplakin (EVPL)
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Alternative Name
- EVPL
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Background
- Background: Envoplakin is a member of the plakin family of proteins that forms a component of desmosomes and the epidermal cornified envelope. The gene is located in the tylosis oesophageal cancer locus on chromosome 17q25, and its deletion is associated with both familial and sporadic forms of oesophageal squamous cell carcinoma. Patients suffering from the autoimmune mucocutaneous disorder, paraneoplastic pemphigus, develop antibodies against Envoplakin [taken from NCBI Entrez Gene (Gene ID: 2125)].
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Gene ID
- 2125
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UniProt
- Q92817
Target
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