Sec8 antibody (AA 1-280)

Catalog No. ABIN6140366

This anti-Sec8 antibody is a Rabbit Polyclonal antibody detecting Sec8 in WB. Suitable for Human.

Quick Overview for Sec8 antibody (AA 1-280) (ABIN6140366)

Target: Sec8 (EXOC4) (Exocyst Complex Component 4 (EXOC4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sec8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Sec8 Antibody

Binding Specificity: AA 1-280

Sequence: MAAEAAGGKY RSTVSKSKDP SGLLISVIRT LSTSDDVEDR ENEKGRLEEA YEKCDRDLDE LIVQHYTELT TAIRTYQSIT ERITNSRNKI KQVKENLLSC KMLLHCKRDE LRKLWIEGIE HKHVLNLLDE IENIKQVPQK LEQCMASKHY LSATDMLVSA VESLEGPLLQ VEGLSDLRLE LHSKKMNLHL VLIDELHRHL YIKSTSRVVQ RNKEKGKISS LVKDASVPLI DVTNLPTPRK FLDTSHYSTA GSSSVREINL QDIKEDLELD PEENSTLFMG

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human EXOC4 (NP_068579.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Sec8

Target: Sec8 (EXOC4) (Exocyst Complex Component 4 (EXOC4))

Alternative Name: EXOC4

Background: The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.,EXOC4,SEC8,SEC8L1,Sec8p,Neuroscience,Cell Type Marker,Neuron marker,Synapse marker,EXOC4

Molecular Weight: 53 kDa/110 kDa

Gene ID: 60412

UniProt: Q96A65

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis