PAR1 antibody (AA 42-110)

Catalog No. ABIN6140404

This Rabbit Polyclonal antibody specifically detects PAR1 in WB. It exhibits reactivity toward Human.

Quick Overview for PAR1 antibody (AA 42-110) (ABIN6140404)

Target: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PAR1 Antibody

Binding Specificity: AA 42-110

Sequence: SFLLRNPNDK YEPFWEDEEK NESGLTEYRL VSINKSSPLQ KQLPAFISED ASGYLTSSWL TLFVPSVYT

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 42-110 of human F2R (NP_001983.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PAR1

Target: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Alternative Name: F2R

Background: Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. Alternative splicing results in multiple transcript variants.,F2R,CF2R,HTR,PAR-1,PAR1,TR,Epigenetics & Nuclear Signaling,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell cycle inhibitors,Cardiovascular,Angiogenesis,Blood,Coagulation,F2R

Molecular Weight: 47 kDa

Gene ID: 2149

UniProt: P25116

Pathways: Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus