FKBP3 antibody (AA 1-224)
Quick Overview for FKBP3 antibody (AA 1-224) (ABIN6140656)
Target
See all FKBP3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-224
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Sequence
- MAAAVPQRAW TVEQLRSEQL PKKDIIKFLQ EHGSDSFLAE HKLLGNIKNV AKTANKDHLV TAYNHLFETK RFKGTESISK VSEQVKNVKL NEDKPKETKS EETLDEGPPK YTKSVLKKGD KTNFPKKGDV VHCWYTGTLQ DGTVFDTNIQ TSAKKKKNAK PLSFKVGVGK VIRGWDEALL TMSKGEKARL EIEPEWAYGK KGQPDAKIPP NAKLTFEVEL VDID
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Cross-Reactivity
- Human
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human FKBP3 (NP_002004.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IP,1:50 - 1:100
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Comment
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))
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Alternative Name
- FKBP3
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Background
- The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.,FKBP3,FKBP-25,FKBP-3,FKBP25,PPIase,Epigenetics & Nuclear Signaling,RNA Binding,FKBP3
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Molecular Weight
- 25 kDa
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Gene ID
- 2287
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UniProt
- Q00688
Target
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