FLCN antibody (AA 1-342)

Catalog No. ABIN6140670

The Rabbit Polyclonal anti-FLCN antibody has been validated for WB and IHC. It is suitable to detect FLCN in samples from Human.

Quick Overview for FLCN antibody (AA 1-342) (ABIN6140670)

Target: FLCN (Folliculin (FLCN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLCN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FLCN Antibody

Binding Specificity: AA 1-342

Sequence: MNAIVALCHF CELHGPRTLF CTEVLHAPLP QGDGNEDSPG QGEQAEEEEG GIQMNSRMRA HSPAEGASVE SSSPGPKKSD MCEGCRSLAA GHPGYISHDK ETSIKYVSHQ HPSHPQLFSI VRQACVRSLS CEVCPGREGP IFFGDEQHGF VFSHTFFIKD SLARGFQRWY SIITIMMDRI YLINSWPFLL GKVRGIIDEL QGKALKVFEA EQFGCPQRAQ RMNTAFTPFL HQRNGNAARS LTSLTSDDNL WACLHTSFAW LLKACGSRLT EKLLEGAPTE DTLVQMEKLA GEAGVLLPGP WPGWPWGGTS CLLSWQESLR EGNAALNQPR TSLREAHPPI SV

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-342 of human FLCN (NP_653207.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FLCN

Target: FLCN (Folliculin (FLCN))

Alternative Name: FLCN

Target Type: Amino Acid

Background: This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms.,FLCN,BHD,FLCL,Cancer,Tumor suppressors,Signal Transduction,PI3K-Akt Signaling Pathway,Regulator of mTOR complex function,FLCN

Molecular Weight: 20 kDa/37 kDa/64 kDa

Gene ID: 201163

UniProt: Q8NFG4

Pathways: Cell-Cell Junction Organization