FOXP3 antibody (AA 180-300)

Catalog No. ABIN6140765

This anti-FOXP3 antibody is a Rabbit Polyclonal antibody detecting FOXP3 in WB. Suitable for Human.

Quick Overview for FOXP3 antibody (AA 180-300) (ABIN6140765)

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXP3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FOXP3 Antibody

Binding Specificity: AA 180-300

Sequence: LKHCQADHLL DEKGRAQCLL QREMVQSLEQ QLVLEKEKLS AMQAHLAGKM ALTKASSVAS SDKGSCCIVA AGSQGPVVPA WSGPREAPDS LFAVRRHLWG SHGNSTFPEF LHNMDYFKFH N

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-300 of human FOXP3 (NP_001107849.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FOXP3

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Alternative Name: FOXP3

Background: The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.,FOXP3,AIID,DIETER,IPEX,JM2,PIDX,XPID,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Cell Cycle,Immunology & Inflammation,FOXP3

Molecular Weight: 43 kDa/44 kDa/47 kDa/49 kDa

Gene ID: 50943

UniProt: Q9BZS1

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation