GCDH antibody (AA 149-438)

Catalog No. ABIN6141009

The Rabbit Polyclonal anti-GCDH antibody has been validated for WB. It is suitable to detect GCDH in samples from Human.

Quick Overview for GCDH antibody (AA 149-438) (ABIN6141009)

Target: GCDH (Glutaryl-CoA Dehydrogenase (GCDH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCDH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GCDH Antibody

Binding Specificity: AA 149-438

Sequence: MHPIYAYGSE EQRQKYLPQL AKGELLGCFG LTEPNSGSDP SSMETRAHYN SSNKSYTLNG TKTWITNSPM ADLFVVWARC EDGCIRGFLL EKGMRGLSAP RIQGKFSLRA SATGMIIMDG VEVPEENVLP GASSLGGPFG CLNNARYGIA WGVLGASEFC LHTARQYALD RMQFGVPLAR NQLIQKKLAD MLTEITLGLH ACLQLGRLKD QDKAAPEMVS LLKRNNCGKA LDIARQARDM LGGNGISDEY HVIRHAMNLE AVNTYEGTHD IHALILGRAI TGIQAFTASK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 149-438 of human GCDH (NP_000150.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GCDH

Target: GCDH (Glutaryl-CoA Dehydrogenase (GCDH))

Alternative Name: GCDH

Background: The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12.,GCDH,ACAD5,GCD,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Amino acid metabolism,GCDH

Molecular Weight: 47 kDa/48 kDa

Gene ID: 2639

UniProt: Q92947