GGCX antibody (AA 479-758)

Catalog No. ABIN6141069

This Rabbit Polyclonal antibody specifically detects GGCX in WB. It exhibits reactivity toward Human.

Quick Overview for GGCX antibody (AA 479-758) (ABIN6141069)

Target: GGCX (gamma-Glutamyl Carboxylase (GGCX))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GGCX antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GGCX Antibody

Binding Specificity: AA 479-758

Sequence: QRIFDPRVDI VQAAWSPFQR TSWVQPLLMD LSPWRAKLQE IKSSLDNHTE VVFIADFPGL HLENFVSEDL GNTSIQLLQG EVTVELVAEQ KNQTLREGEK MQLPAGEYHK VYTTSPSPSC YMYVYVNTTE LALEQDLAYL QELKEKVENG SETGPLPPEL QPLLEGEVKG GPEPTPLVQT FLRRQQRLQE IERRRNTPFH ERFFRFLLRK LYVFRRSFLM TCISLRNLIL GRPSLEQLAQ EVTYANLRPF EAVGELNPSN TDSSHSNPPE SNPDPVHSEF

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 479-758 of human GGCX (NP_000812.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GGCX

Target: GGCX (gamma-Glutamyl Carboxylase (GGCX))

Alternative Name: GGCX

Background: This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate, a modification that is required for their activity. The vitamin K-dependent protein substrates have a propeptide that binds the enzyme, with carbon dioxide, dioxide, and reduced vitamin K acting as co-substrates. Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation, prevention of vascular calcification, and inflammation. Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency. Alternative splicing results in multiple transcript variants.,GGCX,VKCFD1,Cardiovascular,Blood,Coagulation,GGCX

Molecular Weight: 80 kDa/87 kDa

Gene ID: 2677

UniProt: P38435

Pathways: SARS-CoV-2 Protein Interactome