Cx40/GJA5 antibody (AA 229-358)

Catalog No. ABIN6141101

This Rabbit Polyclonal antibody specifically detects Cx40/GJA5 in WB. It exhibits reactivity toward Human.

Quick Overview for Cx40/GJA5 antibody (AA 229-358) (ABIN6141101)

Target: Cx40/GJA5 (GJA5) (Gap Junction Protein, alpha 5, 40kDa (GJA5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cx40/GJA5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cx40/GJA5 Antibody

Binding Specificity: AA 229-358

Sequence: LGWKKIRQRF VKPRQHMAKC QLSGPSVGIV QSCTPPPDFN QCLENGPGGK FFNPFSNNMA SQQNTDNLVT EQVRGQEQTP GEGFIQVRYG QKPEVPNGVS PGHRLPHGYH SDKRRLSKAS SKARSDDLSV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 229-358 of human GJA5 (NP_859054.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Cx40/GJA5

Target: Cx40/GJA5 (GJA5) (Gap Junction Protein, alpha 5, 40kDa (GJA5))

Alternative Name: GJA5

Background: This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described.,GJA5,ATFB11,CX40,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Gap Junctions,Cytoskeleton,Cardiovascular,Heart,Cardiac arrhythmias,GJA5

Molecular Weight: 40 kDa

Gene ID: 2702

UniProt: P36382

Pathways: Cell-Cell Junction Organization