GMP Synthase antibody (AA 394-693)

Catalog No. ABIN6141190

The Rabbit Polyclonal anti-GMP Synthase antibody has been validated for WB and IP. It is suitable to detect GMP Synthase in samples from Human.

Quick Overview for GMP Synthase antibody (AA 394-693) (ABIN6141190)

Target: GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GMP Synthase antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-GMP Synthase Antibody

Binding Specificity: AA 394-693

Sequence: DTELIRKLRE EGKVIEPLKD FHKDEVRILG RELGLPEELV SRHPFPGPGL AIRVICAEEP YICKDFPETN NILKIVADFS ASVKKPHTLL QRVKACTTEE DQEKLMQITS LHSLNAFLLP IKTVGVQGDC RSYSYVCGIS SKDEPDWESL IFLARLIPRM CHNVNRVVYI FGPPVKEPPT DVTPTFLTTG VLSTLRQADF EAHNILRESG YAGKISQMPV ILTPLHFDRD PLQKQPSCQR SVVIRTFITS DFMTGIPATP GNEIPVEVVL KMVTEIKKIP GISRIMYDLT SKPPGTTEWE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 394-693 of human GMPS (NP_003866.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IP,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GMP Synthase

Target: GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))

Alternative Name: GMPS

Background: In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.,GMPS,GATD7,Epigenetics & Nuclear Signaling,GMPS

Molecular Weight: 65 kDa/76 kDa

Gene ID: 8833

UniProt: P49915

Pathways: Ribonucleoside Biosynthetic Process