GPSM2 antibody (AA 380-490)
Quick Overview for GPSM2 antibody (AA 380-490) (ABIN6141365)
Target
See all GPSM2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 380-490
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Sequence
- STNNSIMSEN TEIDSSLNGV RPKLGRRHSM ENMELMKLTP EKVQNWNSEI LAKQKPLIAK PSAKLLFVNR LKGKKYKTNS STKVLQDASN SIDHRIPNSQ RKISADTIGD E
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Cross-Reactivity
- Human, Mouse
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 380-490 of human GPSM2 (NP_037428.3).
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Isotype
- IgG
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Application Notes
- WB,1:1000 - 1:2000
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Comment
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))
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Alternative Name
- GPSM2
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Background
- The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants.,GPSM2,CMCS,DFNB82,LGN,PINS,Signal Transduction,G protein signaling,Cell Biology & Developmental Biology,Cell Cycle,GPSM2
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Molecular Weight
- 76 kDa
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Gene ID
- 29899
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UniProt
- P81274
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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