GUCY1A1 antibody (AA 1-120)

Catalog No. ABIN6141533

The Rabbit Polyclonal anti-GUCY1A1 antibody has been validated for WB and IF. It is suitable to detect GUCY1A1 in samples from Human.

Quick Overview for GUCY1A1 antibody (AA 1-120) (ABIN6141533)

Target: GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GUCY1A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-GUCY1A1 Antibody

Binding Specificity: AA 1-120

Sequence: MFCTKLKDLK ITGECPFSLL APGQVPNESS EEAAGSSESC KATVPICQDI PEKNIQESLP QRKTSRSRVY LHTLAESICK LIFPEFERLN VALQRTLAKH KIKESRKSLE REDFEKTIAE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human GUCY1A3 (NP_000847.2).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:3000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GUCY1A1

Target: GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))

Alternative Name: GUCY1A3

Background: Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.,GUCY1A3,GC-SA3,GUC1A3,GUCA3,GUCSA3,GUCY1A1,MYMY6,Signal Transduction,Cardiovascular,GUCY1A3

Molecular Weight: 70 kDa/77 kDa

Gene ID: 2982

UniProt: Q02108

Pathways: Myometrial Relaxation and Contraction