GUCY2C antibody (AA 24-330)

Catalog No. ABIN6141537

The Rabbit Polyclonal anti-GUCY2C antibody has been validated for WB. It is suitable to detect GUCY2C in samples from Human.

Quick Overview for GUCY2C antibody (AA 24-330) (ABIN6141537)

Target: GUCY2C (Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GUCY2C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GUCY2C Antibody

Binding Specificity: AA 24-330

Sequence: SQVSQNCHNG SYEISVLMMG NSAFAEPLKN LEDAVNEGLE IVRGRLQNAG LNVTVNATFM YSDGLIHNSG DCRSSTCEGL DLLRKISNAQ RMGCVLIGPS CTYSTFQMYL DTELSYPMIS AGSFGLSCDY KETLTRLMSP ARKLMYFLVN FWKTNDLPFK TYSWSTSYVY KNGTETEDCF WYLNALEASV SYFSHELGFK VVLRQDKEFQ DILMDHNRKS NVIIMCGGPE FLYKLKGDRA VAEDIVIILV DLFNDQYFED NVTAPDYMKN VLVLTLSPGN SLLNSSFSRN LSPTKRDFAL AYLNGIL

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-330 of human GUCY2C (NP_004954.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GUCY2C

Target: GUCY2C (Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C))

Alternative Name: GUCY2C

Background: This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive).,GUCY2C,DIAR6,GC-C,GUC2C,MECIL,MUCIL,STAR,Signal Transduction,GUCY2C

Molecular Weight: 123 kDa

Gene ID: 2984

UniProt: P25092