H2AFY antibody (AA 123-372)

Catalog No. ABIN6141569

The Rabbit Polyclonal anti-H2AFY antibody has been validated for WB, IHC and IF. It is suitable to detect H2AFY in samples from Human.

Quick Overview for H2AFY antibody (AA 123-372) (ABIN6141569)

Target: H2AFY (H2A Histone Family, Member Y (H2AFY))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2AFY antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-H2AFY Antibody

Binding Specificity: AA 123-372

Sequence: KLEAIITPPP AKKAKSPSQK KPVSKKAGGK KGARKSKKKQ GEVSKAASAD STTEGTPADG FTVLSTKSLF LGQKLNLIHS EISNLAGFEV EAIINPTNAD IDLKDDLGNT LEKKGGKEFV EAVLELRKKN GPLEVAGAAV SAGHGLPAKF VIHCNSPVWG ADKCEELLEK TVKNCLALAD DKKLKSIAFP SIGSGRNGFP KQTAAQLILK AISSYFVSTM SSSIKTVYFV LFDSESIGIY VQEMAKLDAN

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 123-372 of human H2AFY (NP_613258.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for H2AFY

Target: H2AFY (H2A Histone Family, Member Y (H2AFY))

Alternative Name: H2AFY

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.,H2AFY,H2A.y,H2A/y,H2AF12M,MACROH2A1.1,mH2A1,macroH2A1.2,Epigenetics & Nuclear Signaling,Histones,H2AFY

Molecular Weight: 39 kDa

Gene ID: 9555

UniProt: O75367