HARS2 antibody (AA 217-506)

Catalog No. ABIN6141609

This Rabbit Polyclonal antibody specifically detects HARS2 in WB. It exhibits reactivity toward Human.

Quick Overview for HARS2 antibody (AA 217-506) (ABIN6141609)

Target: HARS2 (Histidyl-tRNA Synthetase 2, Mitochondrial (Putative) (HARS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HARS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HARS2 Antibody

Binding Specificity: AA 217-506

Sequence: IVDGMFAVCG VPESKFRAIC SSIDKLDKMA WKDVRHEMVV KKGLAPEVAD RIGDYVQCHG GVSLVEQMFQ DPRLSQNKQA LEGLGDLKLL FEYLTLFGIA DKISFDLSLA RGLDYYTGVI YEAVLLQTPT QAGEEPLNVG SVAAGGRYDG LVGMFDPKGH KVPCVGLSIG VERIFYIVEQ RMKTKGEKVR TTETQVFVAT PQKNFLQERL KLIAELWDSG IKAEMLYKNN PKLLTQLHYC ESTGIPLVVI IGEQELKEGV IKIRSVASRE EVAIKRENFV AEIQKRLSES

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 217-506 of human HARS2 (NP_036340.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HARS2

Target: HARS2 (Histidyl-tRNA Synthetase 2, Mitochondrial (Putative) (HARS2))

Alternative Name: HARS2

Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes likely share a bidirectional promoter. Mutations in this gene are associated with the pathogenesis of Perrault syndrome, which involves ovarian dysgenesis and sensorineural hearing loss. Alternative splicing results in multiple transcript variants of this gene.,HARS2,HARSL,HARSR,HO3,PRLTS2,Epigenetics & Nuclear Signaling,HARS2

Molecular Weight: 54 kDa/56 kDa

Gene ID: 23438

UniProt: P49590