INPPL1 antibody (AA 100-310)
Quick Overview for INPPL1 antibody (AA 100-310) (ABIN6142475)
Target
See all INPPL1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 100-310
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Sequence
- GLYAQPNQGL VCALLLPVEG EREPDPPDDR DASDGEDEKP PLPPRSGSTS ISAPTGPSSP LPAPETPTAP AAESAPNGLS TVSHDYLKGS YGLDLEAVRG GASHLPHLTR TLATSCRRLH SEVDKVLSGL EILSKVFDQQ SSPMVTRLLQ QQNLPQTGEQ ELESLVLKLS VLKDFLSGIQ KKALKALQDM SSTAPPAPQP STRKAKTIPV Q
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 100-310 of human INPPL1 (NP_001558.3).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Comment
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))
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Alternative Name
- INPPL1
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Background
- The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.,INPPL1,OPSMD,SHIP2,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Growth factor,Endocrine & Metabolism,Lipid Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Neuroscience,Cardiovascular,Angiogenesis,INPPL1
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Molecular Weight
- 113 kDa/138 kDa
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Gene ID
- 3636
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UniProt
- O15357
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Pathways
- Platelet-derived growth Factor Receptor Signaling
Target
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